Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597764 | 0.89 | GABRA1 (0.71) | GABRA1GABRB2TSHRPOLBTYR | |
| SCHEMBL2021492 | 0.84 | GABRA1 (0.45) | GABRA1GABRB2TSHRPOLBTYR | |
| SCHEMBL755644 | 0.80 | TYR (0.66) | GABRA1GABRB2TSHRPOLBTYR | |
| SCHEMBL29366137 | 0.80 | TYR (0.66) | GABRA1GABRB2TSHRPOLBTYR | |
| SCHEMBL3415686 | 0.79 | GABRA1 (0.65) | GABRA1GABRB2TSHRPOLBTYR | |
| SCHEMBL29205217 | 0.78 | KDM4E (0.42) | GABRA1GABRB2TSHRPOLBTYR | |
| SCHEMBL2022379 | 0.78 | GABRA1 (0.58) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL908216 | 0.78 | TAAR1 (0.50) | TSHRKDM4EALDH1A1LMNAHIF1A | |
| SCHEMBL8567329 | 0.77 | GABRA1 (0.62) | GABRA1GABRB2TSHRPOLBTYR | |
| Hydrogen Peroxide SCHEMBL28937397 | 0.77 | GABRA1 (0.95) | GABRA1GABRB2TSHRPOLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ALKBH3, CPS1, APEH | GABRA1 1573/4885GABRB2 1720/4885TSHR 2998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.