Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183645 | 0.84 | PIK3C3 (0.41) | PIK3C3KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL20354225 | 0.82 | KDM4E (0.39) | KDM4EHPGDHSD17B10SMN1; SMN2GAA | |
| SCHEMBL20183852 | 0.74 | PRKDC (0.47) | KDM4EHPGDHSD17B10SMN1; SMN2GAA | |
| SCHEMBL20183547 | 0.73 | GAA (0.47) | KDM4EHPGDHSD17B10SMN1; SMN2GAA | |
| SCHEMBL20354266 | 0.73 | PRKDC (0.54) | KDM4EHPGDHSD17B10SMN1; SMN2GAA | |
| SCHEMBL20183815 | 0.73 | GAA (0.40) | KDM4EHPGDHSD17B10SMN1; SMN2GAA | |
| SCHEMBL20183772 | 0.73 | LYN (0.41) | KDM4EHPGDHSD17B10SMN1; SMN2GAA | |
| SCHEMBL20788143 | 0.73 | KDM4E (0.38) | KDM4EHPGDHSD17B10SMN1; SMN2GAA | |
| SCHEMBL20183749 | 0.73 | NCF1 (0.42) | KDM4EHPGDHSD17B10SMN1; SMN2GAA | |
| SCHEMBL20183597 | 0.72 | GAA (0.46) | KDM4EHPGDHSD17B10SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327004-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3327004-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Fujifilm Corporation (JP) | 2018-05-30 | — | — | EP | disclosed |