Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183483 | 0.92 | ALDH1A1 (0.49) | HTR1DHTR1BKDM4EALDH1A1HPGD | |
| SCHEMBL20183697 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL21549568 | 0.81 | KDM4E (0.39) | HTR1DHTR1BKDM4EALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL21549535 | 0.79 | HTR1D (0.41) | HTR1DHTR1BKDM4EALDH1A1HPGD | |
| SCHEMBL21549489 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL20183750 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL3352752 | 0.76 | HTR1B (0.57) | HTR1DHTR1BDRD2SLC6A4HTR6 | |
| SCHEMBL20183842 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL20183682 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL20183635 | 0.74 | BRD4 (0.43) | KDM4EALDH1A1HPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327004-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3327004-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Fujifilm Corporation (JP) | 2018-05-30 | — | — | EP | disclosed |