SCHEMBL20195231

SCHEMBL20195231

CCn1c(=O)cc(C2CC2)c2cc(N(C)C(=O)c3ccccc3N[S+](C)[O-])ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
RORC P51449 1/20 0.35
NPY5R Q15761 1/20 0.34
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34
HTR3A P46098 1/20 0.34
HTR3D Q70Z44 1/20 0.34
HTR3C Q8WXA8 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HTT P42858 3/20 0.34
KDM4E B2RXH2 3/20 0.33
TSHR P16473 3/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
LMNA P02545 2/20 0.32
CD38 P28907 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20183601 0.89 NPY5R (0.38) ALDH1A1RORCNPY5RHTR3EHTR3B
SCHEMBL20183827 0.87 MEN1 (0.39) ALDH1A1RORCNPY5RHTR3EHTR3B
SCHEMBL20788153 0.86 ALDH1A1 (0.40) ALDH1A1RORCNPY5RHTR3EHTR3B
SCHEMBL20183808 0.85 ATM (0.36) ALDH1A1RORCNPY5RHTR3EHTR3B
SCHEMBL20183494 0.84 ALDH1A1 (0.39) ALDH1A1RORCNPY5RHTR3EHTR3B
SCHEMBL20183481 0.84 KDM4E (0.43) ALDH1A1RORCNPY5RHTR3EHTR3B
SCHEMBL20183797 0.83 ALDH1A1 (0.39) ALDH1A1RORCNPY5RHTR3EHTR3B
SCHEMBL20183742 0.83 ALDH1A1 (0.38) ALDH1A1RORCNPY5RHTR3EHTR3B
SCHEMBL22625701 0.82 ALDH1A1 (0.31) ALDH1A1MEN1KMT2A
SCHEMBL20183880 0.81 ALDH1A1 (0.41) ALDH1A1RORCHTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3327004-B1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND FUJIFILM CORP (JP) 2020-11-04 EP disclosed
EP-3327004-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND Fujifilm Corporation (JP) 2018-05-30 EP disclosed