Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183663 | 0.78 | TSHR (0.41) | METAP2KDM4EHPGDNPSR1GAA | |
| SCHEMBL23253833 | 0.77 | S1PR1 (0.34) | METAP2KDM4EHPGDNPSR1GAA | |
| SCHEMBL20183818 | 0.75 | BRD4 (0.37) | METAP2KDM4EHPGDNPSR1GAA | |
| SCHEMBL20183776 | 0.73 | KMT2A (0.61) | KDM4EHPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL20183547 | 0.70 | GAA (0.47) | METAP2KDM4EHPGDNPSR1GAA | |
| SCHEMBL20354266 | 0.70 | PRKDC (0.54) | KDM4EHPGDNPSR1GAASMN1; SMN2 | |
| SCHEMBL20183733 | 0.70 | HIF1A (0.41) | KDM4EHPGDNPSR1GAASMN1; SMN2 | |
| SCHEMBL20806222 | 0.70 | GAA (0.40) | METAP2KDM4EHPGDNPSR1GAA | |
| SCHEMBL20195167 | 0.70 | PIK3C3 (0.41) | METAP2KDM4EHPGDNPSR1GAA | |
| SCHEMBL23254019 | 0.70 | GAA (0.36) | KDM4EHPGDNPSR1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327004-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3327004-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Fujifilm Corporation (JP) | 2018-05-30 | — | — | EP | disclosed |