Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195426 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| SCHEMBL20195559 | 0.82 | ALDH1A1 (0.43) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL20195550 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| SCHEMBL20195438 | 0.79 | ALDH1A1 (0.42) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL20195451 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL20195598 | 0.77 | KMT2A (0.49) | ALDH1A1RAB9AMEN1KMT2AMAPK1 | |
| SCHEMBL20195435 | 0.77 | ALDH1A1 (0.45) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| SCHEMBL16920877 | 0.77 | MAPT (0.45) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| SCHEMBL18831513 | 0.76 | MEN1 (0.44) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| SCHEMBL20195552 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |