SCHEMBL20195464

SCHEMBL20195464

CN(N)c1cccc(Br)c1CBr

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.32
EED O75530 2/20 0.31
HTR7 P34969 2/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18831297 0.81 HTR1D (0.32) TAAR1HTR7
SCHEMBL19909914 0.80 IDO1 (0.32) TAAR1HTR7
SCHEMBL18831542 0.79 KDM4E (0.40) TAAR1EED
SCHEMBL19909873 0.79 AOC3 (0.41) TAAR1
SCHEMBL19006777 0.79
SCHEMBL18831729 0.79 HPGD (0.31)
SCHEMBL18831302 0.78 GABRA1 (0.41) TAAR1TSHR
SCHEMBL20342845 0.77
SCHEMBL18831567 0.77 AOC3 (0.40) TAAR1HTR7
SCHEMBL18831153 0.75 AOC3 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 EP disclosed
EP-3029038-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2019-03-27 EP disclosed
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed