Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 3/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22037214 | 0.85 | PTGER4 (0.44) | FFAR1KDM4EALDH1A1DHODH | |
| SCHEMBL20195433 | 0.85 | FFAR1 (0.40) | FFAR1GABRA5 | |
| SCHEMBL22038156 | 0.81 | NPC1 (0.39) | FFAR1GABRA5MAPTKDM4E | |
| SCHEMBL22037652 | 0.81 | TDP1 (0.37) | FFAR1 | |
| SCHEMBL22038654 | 0.80 | SMPD1 (0.43) | MAPTKDM4EALDH1A1SGMS2MKNK2 | |
| SCHEMBL22038663 | 0.80 | FFAR4 (0.42) | FFAR1MAPTALDH1A1 | |
| SCHEMBL22038173 | 0.79 | MRGPRX4 (0.39) | FFAR1 | |
| SCHEMBL22038158 | 0.78 | MEN1 (0.36) | FFAR1GABRA5MAPTKDM4EALDH1A1 | |
| SCHEMBL22038670 | 0.78 | PTGER4 (0.40) | FFAR1KDM4EALDH1A1 | |
| SCHEMBL22037630 | 0.78 | MRGPRX4 (0.46) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |