SCHEMBL20195433

SCHEMBL20195433

Cc1cccc(N(N)C(=O)NN)c1COc1ccc(-c2ccccc2)cn1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.40
GABRA5 P31644 13/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20195467 0.85 FFAR1 (0.42) FFAR1GABRA5
SCHEMBL22038158 0.83 MEN1 (0.36) FFAR1GABRA5
SCHEMBL22037214 0.82 PTGER4 (0.44) FFAR1
SCHEMBL22038156 0.82 NPC1 (0.39) FFAR1GABRA5
SCHEMBL22038746 0.80 OXTR (0.41) FFAR1
SCHEMBL22038173 0.80 MRGPRX4 (0.39) FFAR1
SCHEMBL22037652 0.80 TDP1 (0.37) FFAR1
SCHEMBL22038663 0.78 FFAR4 (0.42) FFAR1
SCHEMBL20195508 0.78 FFAR1 (0.36) FFAR1GABRA5
SCHEMBL22564091 0.78 NR1H4 (0.38) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed