Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195550 | 0.89 | ALDH1A1 (0.49) | ALDH1A1TDP1KMT2AL3MBTL1MEN1 | |
| SCHEMBL20195567 | 0.82 | KMT2A (0.49) | ALDH1A1TDP1KMT2AL3MBTL1MEN1 | |
| SCHEMBL20195582 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18185050 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TDP1KMT2AL3MBTL1MEN1 | |
| SCHEMBL22564431 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TDP1KMT2AL3MBTL1MEN1 | |
| SCHEMBL18504143 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TDP1KMT2AL3MBTL1MEN1 | |
| SCHEMBL20195565 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18185022 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TDP1KMT2AL3MBTL1MEN1 | |
| SCHEMBL20195648 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1KMT2ANPC1RAB9A | |
| SCHEMBL8342103 | 0.76 | KMT2A (0.54) | ALDH1A1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |