Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024000 | 0.91 | KDM4E (0.50) | DDR1ALDH1A1KDM4EKITATM | |
| SCHEMBL374710 | 0.89 | NR1H2 (0.57) | DDR1ALDH1A1KDM4EKITNR1H2 | |
| SCHEMBL16380701 | 0.88 | DDR1 (0.52) | DDR1ALDH1A1KDM4ENPSR1KIT | |
| SCHEMBL3568167 | 0.87 | ALDH1A1 (0.47) | DDR1ALDH1A1KDM4ENPSR1KIT | |
| SCHEMBL3565052 | 0.87 | ALDH1A1 (0.47) | DDR1ALDH1A1KDM4ENPSR1KIT | |
| SCHEMBL20196179 | 0.85 | ALDH1A1 (0.44) | DDR1ALDH1A1KDM4EKCNH2HRH3 | |
| SCHEMBL16528525 | 0.84 | ALDH1A1 (0.47) | DDR1ALDH1A1KDM4EKITATM | |
| SCHEMBL20196015 | 0.84 | DDR1 (0.46) | DDR1ALDH1A1KCNH2HRH3NPC1 | |
| SCHEMBL3020407 | 0.82 | CYP2D6 (0.52) | DDR1ALDH1A1KDM4ENPSR1KIT | |
| SCHEMBL16380700 | 0.81 | DDR1 (0.50) | DDR1ALDH1A1KDM4ENPSR1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842939-B1 | BENZAMIDE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |