Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2828911 | 0.79 | NPC1 (0.45) | NPC1 | |
| SCHEMBL10010445 | 0.71 | — | — | |
| SCHEMBL1496 | 0.71 | — | — | |
| SCHEMBL7065026 | 0.69 | GSTP1 (0.39) | NPC1 | |
| SCHEMBL3203754 | 0.69 | — | — | |
| SCHEMBL1401583 | 0.64 | NPC1 (0.48) | NPC1 | |
| SCHEMBL291486 | 0.64 | NPC1 (0.48) | NPC1 | |
| SCHEMBL15583801 | 0.63 | NPC1 (0.43) | NPC1 | |
| SCHEMBL2241578 | 0.62 | — | — | |
| SCHEMBL291487 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8221775-B2 | Pyrrolin-2-ylamino compounds for combating animal pests | BASF SE (DE) | 2012-07-17 | — | — | US | disclosed |
| US-8211924-B2 | 1-(azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests | BASF SE (DE) | 2012-07-03 | — | — | US | disclosed |
| EP-2346822-A1 | PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | BASF SE | 2011-06-30 | — | — | US | disclosed |
| US-20100280078-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests | BASF SE (DE) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | RXFP3, CBR3, ATL3 | NPC1 1162/4885 |
| US-20100280078-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests | NR0B1, NR0B2, NR2C2 | NPC1 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.