Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CFB | P00751 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30596550 | 0.87 | KDM4E (0.70) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL806920 | 0.87 | CFB (0.53) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL10211060 | 0.85 | CFB (0.50) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL17857251 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL807423 | 0.77 | ALDH1A1 (0.51) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL29253343 | 0.76 | CFB (0.43) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11211349 | 0.76 | CYP2D6 (0.51) | KDM4EALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL14667062 | 0.75 | DPP7 (0.51) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL29941203 | 0.75 | ALDH1A1 (1.00) | KDM4EALDH1A1POLBCYP2A13CYP2D6 | |
| SCHEMBL2107499 | 0.73 | ALDH1A1 (0.96) | KDM4EALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842939-B1 | BENZAMIDE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |