Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748175 | 0.81 | ERN1 (0.66) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL15358010 | 0.77 | ERN1 (0.50) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL20196189 | 0.77 | ERN1 (0.50) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL27889697 | 0.74 | ERN1 (0.57) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL30973586 | 0.73 | ERN1 (0.55) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL28293621 | 0.72 | ERN1 (0.68) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL15898932 | 0.72 | ERN1 (0.46) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL5883425 | 0.70 | KDM4E (0.66) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL6090664 | 0.70 | ERN1 (0.51) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL3664240 | 0.69 | ERN1 (0.50) | ERN1PRKDCALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842939-B1 | BENZAMIDE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |