Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13896057 | 0.80 | THRB (0.32) | MAPTCA1CA2CA4CA7 | |
| SCHEMBL11497979 | 0.79 | — | — | |
| SCHEMBL22606192 | 0.79 | MAPT (0.35) | MAPTCA1CA2CA4CA7 | |
| SCHEMBL23565834 | 0.75 | MAPT (0.33) | MAPT | |
| SCHEMBL23680111 | 0.74 | — | — | |
| SCHEMBL7280355 | 0.73 | — | — | |
| SCHEMBL25735085 | 0.72 | MAPT (0.31) | MAPT | |
| SCHEMBL13075841 | 0.71 | MEN1 (0.38) | MAPTCA1CA2CA4CA7 | |
| SCHEMBL8750612 | 0.69 | MAPT (0.30) | MAPT | |
| SCHEMBL26529058 | 0.68 | MAPT (0.35) | MAPTCA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327027-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | Pfizer Inc (US) | 2018-05-30 | — | — | EP | disclosed |