Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 7/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19647231 | 1.00 | ATM (0.41) | ATML3MBTL1GAARENSSTR2 | |
| SCHEMBL21699253 | 1.00 | ATM (0.41) | ATML3MBTL1GAARENSSTR2 | |
| SCHEMBL20054942 | 1.00 | ATM (0.41) | ATML3MBTL1GAARENSSTR2 | |
| SCHEMBL21699555 | 1.00 | ATM (0.41) | ATML3MBTL1GAARENSSTR2 | |
| SCHEMBL19393925 | 0.95 | ACE (0.39) | ATML3MBTL1SSTR2ALDH1A1HSD17B10 | |
| SCHEMBL24837234 | 0.94 | SSTR2 (0.39) | ATML3MBTL1GAARENSSTR2 | |
| SCHEMBL24201016 | 0.94 | SSTR2 (0.39) | ATML3MBTL1GAARENSSTR2 | |
| SCHEMBL20634215 | 0.94 | ATM (0.43) | ATML3MBTL1GAARENSSTR2 | |
| SCHEMBL14978847 | 0.94 | ATM (0.43) | ATML3MBTL1GAARENSSTR2 | |
| SCHEMBL20228064 | 0.93 | ATM (0.40) | ATML3MBTL1GAARENSSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607996-B1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2023-01-04 | — | — | EP | disclosed |
| EP-3388427-B1 | DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS | PF MEDICAMENT (FR) | 2022-01-19 | — | — | EP | disclosed |
| EP-3607996-A1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2020-02-12 | — | — | EP | disclosed |
| EP-3327027-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | Pfizer Inc (US) | 2018-05-30 | — | — | EP | disclosed |