Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | CTSE | P14091 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 3/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24837234 | 1.00 | SSTR2 (0.39) | SSTR2ATML3MBTL1CYP3A4REN | |
| SCHEMBL24837336 | 0.96 | SSTR2 (0.38) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL24201085 | 0.96 | SSTR2 (0.38) | SSTR2CYP3A4CTSDCTSEBACE1 | |
| SCHEMBL20196483 | 0.94 | ATM (0.41) | SSTR2ATML3MBTL1CYP3A4REN | |
| SCHEMBL21699253 | 0.94 | ATM (0.41) | SSTR2ATML3MBTL1CYP3A4REN | |
| SCHEMBL21699555 | 0.94 | ATM (0.41) | SSTR2ATML3MBTL1CYP3A4REN | |
| SCHEMBL19647231 | 0.94 | ATM (0.41) | SSTR2ATML3MBTL1CYP3A4REN | |
| SCHEMBL20054942 | 0.94 | ATM (0.41) | SSTR2ATML3MBTL1CYP3A4REN | |
| SCHEMBL21444786 | 0.93 | ATM (0.38) | SSTR2ATML3MBTL1CYP3A4REN | |
| SCHEMBL21699534 | 0.93 | SSTR2 (0.38) | SSTR2ATML3MBTL1CYP3A4REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388427-B1 | DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS | PF MEDICAMENT (FR) | 2022-01-19 | — | — | EP | disclosed |