Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19703600 | 0.80 | MGLL (0.51) | MGLLCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19703726 | 0.80 | MGLL (0.51) | MGLLCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17740198 | 0.78 | MGLL (0.49) | MGLLCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19698198 | 0.78 | MGLL (0.49) | MGLLCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17739988 | 0.78 | MGLL (0.49) | MGLLCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17739917 | 0.78 | MGLL (0.59) | MGLLKMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL19703587 | 0.77 | MGLL (0.54) | MGLLHPGDSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL19703601 | 0.76 | MGLL (0.49) | MGLLKMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL17739588 | 0.75 | MGLL (0.51) | MGLLKMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL19698113 | 0.75 | MGLL (0.48) | MGLLKMT2AHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327027-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | Pfizer Inc (US) | 2018-05-30 | — | — | EP | disclosed |