Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27252494 | 0.91 | TDP1 (0.51) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL17723069 | 0.89 | TDP1 (0.46) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL9888101 | 0.88 | MEN1 (0.46) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL13538023 | 0.88 | MEN1 (0.46) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL14727558 | 0.88 | MEN1 (0.47) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL12318111 | 0.88 | MEN1 (0.47) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL14653705 | 0.86 | TDP1 (0.46) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL21361575 | 0.86 | TDP1 (0.46) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL30827631 | 0.85 | TDP1 (0.46) | TDP1MEN1GAAKMT2ASYK | |
| SCHEMBL13045906 | 0.85 | CTSK (0.48) | TDP1MEN1GAAKMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |