Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203948 | 0.87 | PPARA (0.48) | PPARAPPARGEPHX2HDAC3HDAC4 | |
| SCHEMBL10383314 | 0.87 | PPARA (0.48) | PPARAPPARGEPHX2HDAC3HDAC4 | |
| SCHEMBL10419405 | 0.86 | PPARA (0.47) | PPARAPPARGEPHX2HDAC3HDAC4 | |
| SCHEMBL20196995 | 0.86 | LTB4R (0.39) | PPARAALDH1A1 | |
| SCHEMBL11205312 | 0.84 | PPARA (0.52) | PPARAPPARGEPHX2HDAC3HDAC4 | |
| SCHEMBL10419197 | 0.84 | PPARA (0.46) | PPARAPPARGEPHX2HDAC3HDAC4 | |
| SCHEMBL10384991 | 0.84 | PPARA (0.52) | PPARAPPARGEPHX2HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL10419505 | 0.84 | SPHK1 (0.46) | PPARAPPARGEPHX2HDAC3HDAC4 | |
| SCHEMBL28578770 | 0.84 | SMN1; SMN2 (0.52) | MAPTLMNATDP1ALOX5 | |
| SCHEMBL10419279 | 0.83 | PPARA (0.45) | PPARAPPARGEPHX2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |