Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24106624 | 0.68 | — | — | |
| SCHEMBL13858888 | 0.67 | OPRM1 (0.58) | OPRM1SPHK1TP53ADH1BADH1C | |
| SCHEMBL9440004 | 0.67 | OPRM1 (0.39) | OPRM1SPHK1TP53 | |
| SCHEMBL13858988 | 0.65 | OPRM1 (0.55) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL325629 | 0.65 | OPRM1 (0.55) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL31169240 | 0.65 | OPRM1 (0.55) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL10657571 | 0.65 | OPRM1 (0.55) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL11486416 | 0.65 | OPRM1 (0.55) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL11480610 | 0.65 | OPRM1 (0.55) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL11469974 | 0.65 | OPRM1 (0.55) | OPRM1SPHK1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |