Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197195 | 0.80 | ALDH1A1 (0.33) | HTR2CMAPK1MAPT | |
| SCHEMBL26389404 | 0.79 | — | — | |
| SCHEMBL6154816 | 0.77 | MAPK1 (0.47) | GRM2PIK3CDLMNAMAPK1 | |
| SCHEMBL20548194 | 0.76 | — | — | |
| SCHEMBL23138107 | 0.75 | S1PR1 (0.34) | GRM2PIK3CDLMNAHTR2AHTR2C | |
| SCHEMBL18250270 | 0.75 | MAPK1 (0.34) | GRM2PIK3CDLMNAHTR2AHTR2C | |
| SCHEMBL22633135 | 0.75 | KDM4E (0.48) | GRM2PIK3CDLMNAHTR2AHTR2C | |
| SCHEMBL27038548 | 0.75 | GRM2 (0.41) | GRM2PIK3CDLMNACNR2CTSK | |
| SCHEMBL16502339 | 0.73 | BAZ2A (0.37) | GRM2PIK3CDLMNACNR2CTSK | |
| SCHEMBL26389411 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |