Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29851369 | 0.78 | FDPS (0.59) | MAPK14MAPK10HRH4FDPSTRPM8 | |
| SCHEMBL828257 | 0.78 | FDPS (0.59) | MAPK14MAPK10HRH4FDPSTRPM8 | |
| SCHEMBL20197172 | 0.76 | MAPK14 (0.42) | MAPK14MAPK10HRH4FDPSTRPM8 | |
| SCHEMBL15102638 | 0.76 | MAPK14 (0.42) | MAPK14MAPK10HRH4FDPSTRPM8 | |
| SCHEMBL26547688 | 0.76 | MAPK14 (0.42) | MAPK14MAPK10HRH4FDPSTRPM8 | |
| SCHEMBL23066110 | 0.76 | MAPK14 (0.47) | MAPK14MAPK10HRH4FDPSTRPM8 | |
| SCHEMBL26686513 | 0.76 | SMN1; SMN2 (0.45) | MAPK14MAPK10HRH4FDPSTRPM8 | |
| SCHEMBL12356613 | 0.76 | MAPK14 (0.42) | MAPK14MAPK10HRH4FDPSTRPM8 | |
| SCHEMBL17131640 | 0.76 | MAPK14 (0.52) | MAPK14MAPK10HRH4 | |
| SCHEMBL24815412 | 0.74 | HRH4 (0.44) | MAPK14MAPK10HRH4FDPSTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |