Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | MAOA | P21397 | 7/20 | 0.44 |
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11482528 | 1.00 | GAA (0.68) | GAAMAPTBRD4MAOBMAOA | |
| SCHEMBL449180 | 0.90 | MAPT (0.82) | GAAMAPTBRD4LMNAMAP1LC3B | |
| SCHEMBL11483101 | 0.86 | GAA (0.57) | GAAMAPTBRD4MAOBMAOA | |
| SCHEMBL16581527 | 0.86 | MAPT (0.57) | GAAMAPTBRD4MAOBMAOA | |
| SCHEMBL7945655 | 0.82 | GAA (0.53) | GAAMAPTBRD4MAOBMAOA | |
| SCHEMBL562614 | 0.81 | MAPT (1.00) | GAAMAPTBRD4LMNAMAP1LC3B | |
| Formic Acid SCHEMBL27499639 | 0.80 | GAA (0.67) | GAAMAPTBRD4AKR1C1MAP1LC3B | |
| SCHEMBL2766491 | 0.79 | SLC18A3 (0.52) | GAAMAPTMAOBMAOAKDM1A | |
| SCHEMBL11661537 | 0.79 | SLC18A3 (0.52) | GAAMAPTMAOBMAOAKDM1A | |
| SCHEMBL2385483 | 0.78 | TP53 (0.50) | GAAMAPTBRD4KDM1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001593-B2 | Rigid dinitroxide biradical compounds used as improved polarizing agents for dynamic nuclear polarization techniques | UNIVERSITE D'AIX-MARSEILLE (FR) | 2021-05-11 | — | — | US | disclosed |
| EP-2986613-B1 | RIGID DINITROXIDE BIRADICAL COMPOUNDS USED AS IMPROVED POLARISING AGENTS FOR DYNAMIC NUCLEAR POLARISATION TECHNIQUES | UNIV AIX MARSEILLE (FR) | 2018-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11001593-B2 | Rigid dinitroxide biradical compounds used as improved polarizing agents for dynamic nuclear polarization techniques | CCNO, CCNA1, CCND1 | GAA 4418/4885MAPT 4785/4885BRD4 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.