SCHEMBL2385483

SCHEMBL2385483

O=C1CC2CC(C1)c1ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.50
RECQL P46063 1/20 0.50
CHRNB4 P30926 1/20 0.50
CHRNA3 P32297 1/20 0.50
MAPT P10636 3/20 0.46
GAA P10253 1/20 0.46
ANPEP P15144 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM1A O60341 2/20 0.35
KDM1B Q8NB78 1/20 0.35
MTNR1A P48039 1/20 0.35
BRD4 O60885 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384404 0.80 MAP1LC3B (0.54) MAPTKMT2ATDP1MEN1ALDH1A1
SCHEMBL20197630 0.78 GAA (0.68) MAPTGAAKMT2AKDM1AKDM1B
SCHEMBL11482528 0.78 GAA (0.68) MAPTGAAKMT2AKDM1AKDM1B
SCHEMBL13116631 0.78 CHRNB2 (0.54) TP53RECQLMAPTGAAANPEP
SCHEMBL427764 0.75 TP53 (0.85) TP53RECQLMAPTGAAKDM4E
SCHEMBL7291465 0.75 CHRNB4 (0.40) TP53RECQLCHRNB4CHRNA3MAPT
SCHEMBL28571106 0.75 BRD4 (0.56) TP53RECQLMAPTGAANPC1
SCHEMBL425265 0.75 KDM1A (0.50) TP53RECQLMAPTGAAKMT2A
SCHEMBL426358 0.75 HTR2C (0.52) TP53RECQLMAPTGAAKMT2A
SCHEMBL23797352 0.73 CHRNB4 (0.59) CHRNB4CHRNA3CHRNB2CHRNA4KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2371911-B1 Active radiation curable ink composition for inkjet recording, printed matter, method of manufacturing printed matter, molded article of printed matter, and method of manufacturing molded article of printed matter FUJIFILM CORP (JP) 2014-03-05 EP disclosed
US-8642680-B2 Active radiation curable ink composition for inkjet recording, printed matter, method of manufacturing printed matter, molded article of printed matter, and method of manufacturing molded article of printed matter FUJIFILM CORPORATION (JP) 2014-02-04 US disclosed
EP-2371911-A1 Active radiation curable ink composition for inkjet recording, printed matter, method of manufacturing printed matter, molded article of printed matter, and method of manufacturing molded article of printed matter Fujifilm Corporation (JP) 2011-10-05 EP disclosed
US-20110236650-A1 ACTIVE RADIATION CURABLE INK COMPOSITION FOR INKJET RECORDING, PRINTED MATTER, METHOD OF MANUFACTURING PRINTED MATTER, MOLDED ARTICLE OF PRINTED MATTER, AND METHOD OF MANUFACTURING MOLDED ARTICLE OF PRINTED MATTER FUJIFILM CORPORATION (JP) 2011-09-29 US disclosed