SCHEMBL2019776

SCHEMBL2019776

COc1ccc(C(=CC(=O)O)c2ccc(OC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.61
CA2 P00918 5/20 0.61
CES2 O00748 2/20 0.57
CES1 P23141 2/20 0.57
ALDH1A1 P00352 3/20 0.55
MAPT P10636 2/20 0.55
KDM4E B2RXH2 1/20 0.55
HPGD P15428 1/20 0.55
PARP1 P09874 1/20 0.53
PARP10 Q53GL7 1/20 0.53
PARP2 Q9UGN5 1/20 0.53
PARP4 Q9UKK3 1/20 0.53
THRB P10828 1/20 0.52
ATM Q13315 1/20 0.52
CYP1A2 P05177 2/20 0.51
PLK1 P53350 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
MEN1 O00255 1/20 0.49
HSPD1 P10809 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4394754 0.94 CES2 (0.65) CA1CA2CES2CES1ALDH1A1
SCHEMBL4394758 0.94 CES2 (0.65) CA1CA2CES2CES1ALDH1A1
SCHEMBL4390225 0.94 CES2 (0.65) CA1CA2CES2CES1ALDH1A1
SCHEMBL8937287 0.88 CA1 (0.49) CA1CA2CES2CES1ALDH1A1
SCHEMBL14034141 0.88 MAPT (0.62) CA1CA2CES2CES1ALDH1A1
SCHEMBL8937283 0.88 CA1 (0.49) CA1CA2CES2CES1ALDH1A1
SCHEMBL8937285 0.88 CA1 (0.49) CA1CA2CES2CES1ALDH1A1
SCHEMBL8937240 0.87 CA1 (0.47) CA1CA2CES2CES1ALDH1A1
SCHEMBL8937361 0.87 HPGD (0.50) CA1CA2CES2CES1ALDH1A1
SCHEMBL8937315 0.87 HPGD (0.50) CA1CA2CES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847784-B1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORP (US) 2017-07-05 EP claimed
EP-0514491-B1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL BETA, BETA-DIPHENYLACRYLATE OR AN ALKYL ALPHA-CYANO-BETA, BETA-DIPHENYLACRYLATE OREAL (FR) 1993-11-03 EP claimed
WO-1991011989-A1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL β, β-DIPHENYLACRYLATE OR AN ALKYL α-CYANO-β, β-DIPHENYLACRYLATE L'OREAL (FR) 1991-08-22 WO claimed
EP-4302746-A1 SYSTEM FOR DISPENSING A COSMETIC PRODUCT L'OREAL (FR) 2024-01-10 EP disclosed
EP-4286038-A2 DISTRIBUTION SYSTEM OF A COSMETIC PRODUCT L'OREAL (FR) 2023-12-06 EP disclosed
EP-1626046-B1 Photochromic oxazine compounds and methods for their manufacture ESSILOR INT (FR) 2014-11-19 EP disclosed
EP-1458695-B1 Method for the manufacture of photochromic oxazine compounds and compounds obtainable therefrom ESSILOR INT (FR) 2012-10-03 EP disclosed
US-8263050-B2 Method of quenching electronic excitation of chromophore-containing organic molecules in photoactive compositions HALLSTAR INNOVATIONS CORP. (US) 2012-09-11 US disclosed
US-7959834-B2 Alkoxycrylene/metal oxide photostabilized photoactive compositions and methods HALLSTAR INNOVATIONS CORP. (US) 2011-06-14 US disclosed
US-20100283015-A1 Alkoxycrylene/Metal Oxide Photostabilized Photoactive Compositions and Methods HALLSTAR INNOVATIONS CORP. (US) 2010-11-11 US disclosed
US-7713519-B2 Method of quenching electronic excitation of chromophore-containing organic molecules in photoactive compositions HALLSTAR INNOVATIONS CORP. (US) 2010-05-11 US disclosed
US-5064848-A Anticoagulants EISAI CO., LTD. (JP) 1991-11-12 US disclosed
WO-1991011989-A1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL β, β-DIPHENYLACRYLATE OR AN ALKYL α-CYANO-β, β-DIPHENYLACRYLATE L'OREAL (FR) 1991-08-22 WO disclosed
EP-0441226-A1 (cyanomethyl)pyridines useful as PAF antagonists J. URIACH & CIA. S.A. (ES) 1991-08-14 EP disclosed
US-5034418-A Anticoagulants EISAI CO., LTD. (JP) 1991-07-23 US disclosed
US-4978767-A ANTICOAGULANTS EISAI CO., LTD. (JP) 1990-12-18 US disclosed
EP-0395446-A2 N-acryloylpiperazine derivatives, their preparation and their use as paf antagonists Sankyo Company Limited (JP) 1990-10-31 EP disclosed
US-4954523-A ANTICOAGULANT EISAI CO., LTD. (JP) 1990-09-04 US disclosed
US-4886834-A ANTICOAGULANTS EISAI CO., LTD. (JP) 1989-12-12 US disclosed
EP-0238973-A2 Diphenyl-methane derivative, pharmaceutical composition and use Eisai Co., Ltd. (JP) 1987-09-30 EP disclosed