SCHEMBL20198157

SCHEMBL20198157

CC(=O)c1ccc(Br)c(C)n1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.42
NPC1 O15118 8/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.40
LMNA P02545 1/20 0.40
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTT P42858 1/20 0.36
KDM1A O60341 1/20 0.36
MAPT P10636 2/20 0.35
IRAK4 Q9NWZ3 1/20 0.34
DHODH Q02127 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30845964 1.00 RAB9A (0.42) RAB9ANPC1KMT2AALDH1A1MAPK1
SCHEMBL1425108 0.83 KDM4E (0.56) RAB9ANPC1KMT2AALDH1A1MAPK1
SCHEMBL22467460 0.82 RAB9A (0.44) RAB9ANPC1KMT2AALDH1A1MAPK1
Hydrochloric Acid SCHEMBL29154171 0.82 KDM4E (0.55) RAB9ANPC1KMT2AALDH1A1MAPK1
SCHEMBL153746 0.82 RAB9A (0.41) RAB9ANPC1KMT2AALDH1A1MAPK1
SCHEMBL15094137 0.79 MAPT (0.47) RAB9ANPC1KMT2AALDH1A1MAPK1
SCHEMBL18348115 0.79 KDM4A (0.42) RAB9ANPC1KMT2AALDH1A1MAPK1
SCHEMBL31033036 0.79 RAB9A (0.39) RAB9ANPC1KMT2AALDH1A1MAPK1
SCHEMBL22912737 0.79 RAB9A (0.46) RAB9ANPC1KMT2AALDH1A1MAPK1
SCHEMBL30356976 0.79 KDM4A (0.42) RAB9ANPC1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-29 US disclosed
EP-4482587-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-01-01 EP disclosed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 WO disclosed
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 WO disclosed
EP-3326627-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME Abide Therapeutics, Inc. (US) 2018-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP RAB9A 3984/4885NPC1 1319/4885KMT2A 3863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.