Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20198295 | 0.96 | HPGD (0.50) | HPGDMAPTPOLBMEN1KMT2A | |
| SCHEMBL4402340 | 0.90 | HPGD (0.56) | HPGDMAPTPOLBMEN1KMT2A | |
| SCHEMBL12792085 | 0.86 | LMNA (0.50) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL83200 | 0.86 | HPGD (0.61) | HPGDMAPTPOLBMEN1KMT2A | |
| SCHEMBL4403188 | 0.86 | HPGD (0.61) | HPGDMAPTPOLBMEN1KMT2A | |
| SCHEMBL4402281 | 0.86 | HPGD (0.61) | HPGDMAPTPOLBMEN1KMT2A | |
| SCHEMBL17928368 | 0.86 | HPGD (0.61) | HPGDMAPTPOLBMEN1KMT2A | |
| SCHEMBL18780701 | 0.82 | HPGD (0.59) | HPGDMAPTPOLBMEN1KMT2A | |
| SCHEMBL26377046 | 0.81 | PTPN5 (0.51) | HPGDMAPTPOLBMEN1KMT2A | |
| Triphenylphosphine Oxide SCHEMBL29014409 | 0.80 | LMNA (0.58) | HPGDMAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |