SCHEMBL20198486

SCHEMBL20198486

C=C(C)c1ccc(-c2nnc(-c3ccc(-c4ccccc4)cc3)n2-c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.61
HPGD P15428 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
MAPT P10636 1/20 0.49
OXTR P30559 1/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
GLA P06280 1/20 0.47
OPRD1 P41143 1/20 0.46
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CDC25A P30304 1/20 0.43
CDC25B P30305 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13324415 0.84 AVPR1A (0.56) AVPR1AHPGDSMN1; SMN2MAPTOXTR
SCHEMBL12110445 0.83 AVPR1A (0.73) AVPR1AHPGDSMN1; SMN2MAPTOXTR
SCHEMBL4402535 0.83 AVPR1A (0.78) AVPR1AHPGDSMN1; SMN2OXTRKDM4E
SCHEMBL8339889 0.83 AVPR1A (0.78) AVPR1AHPGDSMN1; SMN2OXTRKDM4E
SCHEMBL2620730 0.81 AVPR1A (0.70) AVPR1AHPGDSMN1; SMN2MAPTOXTR
SCHEMBL12593291 0.79 AVPR1A (0.67) AVPR1AHPGDSMN1; SMN2MAPTOXTR
SCHEMBL28320964 0.79 AVPR1A (0.71) AVPR1AHPGDSMN1; SMN2OXTRKDM4E
SCHEMBL4502407 0.79 SMN1; SMN2 (0.60) HPGDSMN1; SMN2MAPTKDM4EALDH1A1
SCHEMBL39449 0.79 AVPR1A (0.70) AVPR1AHPGDSMN1; SMN2OXTRKDM4E
SCHEMBL18327898 0.79 AVPR1A (0.70) AVPR1AHPGDSMN1; SMN2OXTRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US disclosed
EP-2496591-B1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2018-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME HCN4, SLC46A1, FES AVPR1A 4746/4885HPGD 3093/4885SMN1; SMN2 3452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.