SCHEMBL20198526

SCHEMBL20198526

NC12CCCCCCC(CCCC1)C2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
GRIN1 Q05586 3/20 0.39
GRIN2A Q12879 3/20 0.39
SLC22A1 O15245 2/20 0.39
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
NFKB1 P19838 2/20 0.39
GRIN2B Q13224 2/20 0.39
GRIN2C Q14957 2/20 0.39
GRIN3A Q8TCU5 2/20 0.39
SLC22A2 O15244 1/20 0.39
TSHR P16473 1/20 0.39
STAT6 P42226 1/20 0.39
SLC47A1 Q96FL8 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
PMP22 Q01453 2/20 0.38
POLB P06746 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21656690 1.00 LMNA (0.39) LMNAGRIN1GRIN2ASLC22A1GRIN2D
SCHEMBL5529161 0.89 LMNA (0.43) LMNAGRIN1GRIN2ASLC22A1GRIN2D
SCHEMBL7037484 0.86 LMNA (0.41) LMNAGRIN1GRIN2ASLC22A1GRIN2D
SCHEMBL9951776 0.84
SCHEMBL31265072 0.78
SCHEMBL301312 0.77
Hydrochloric Acid SCHEMBL23877623 0.75
SCHEMBL9199171 0.74
SCHEMBL20663016 0.67 SLC22A2 (0.30) LMNAGRIN1GRIN2ASLC22A1GRIN2D
Methane SCHEMBL16654784 0.66 LMNA (0.37) LMNAGRIN1GRIN2ASLC22A1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3327603-A1 METHOD AND DEVICE FOR CALCULATING ACID DISSOCIATION CONSTANT, AND PROGRAM Fujitsu Limited (JP) 2018-05-30 EP disclosed