Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20175138 | 0.97 | PDK2 (0.33) | ALKPLA2G2APLA2G4APDK2 | |
| SCHEMBL20175135 | 0.94 | ALK (0.32) | ALKPLA2G2APLA2G4A | |
| SCHEMBL20175136 | 0.92 | PDK2 (0.34) | ALKPLA2G2APLA2G4APDK2 | |
| SCHEMBL20175131 | 0.92 | PDK2 (0.34) | ALKPLA2G2APLA2G4APDK2 | |
| SCHEMBL20174918 | 0.92 | PDK2 (0.34) | ALKPLA2G2APLA2G4ATNKSPTPN1 | |
| SCHEMBL20175091 | 0.91 | ALK (0.31) | ALKPDK2 | |
| SCHEMBL20175227 | 0.91 | PDK2 (0.36) | ALKPLA2G2APLA2G4ATNKSPDK2 | |
| SCHEMBL20175146 | 0.91 | ALK (0.33) | ALK | |
| SCHEMBL20174902 | 0.90 | PDK2 (0.33) | ALKPLA2G2APLA2G4APDK2 | |
| SCHEMBL20175140 | 0.89 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781366-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-09-22 | — | — | US | disclosed |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10781366-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | ALK 2665/4885PLA2G2A 4788/4885PLA2G4A 4802/4885 |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | ALK 2665/4885PLA2G2A 4788/4885PLA2G4A 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.