Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 19/20 | 0.52 |
| ▸ | TDO2 | P48775 | 3/20 | 0.48 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015025 | 0.91 | IDO1 (0.54) | IDO1TDO2IDO2CYP3A4CYP2C9 | |
| SCHEMBL20199032 | 0.90 | IDO1 (0.50) | IDO1TDO2IDO2CYP3A4CYP2C9 | |
| SCHEMBL19133468 | 0.89 | IDO1 (0.52) | IDO1TDO2IDO2CYP3A4CYP2C9 | |
| SCHEMBL19158107 | 0.89 | IDO1 (0.52) | IDO1TDO2IDO2CYP3A4CYP2C9 | |
| SCHEMBL20653587 | 0.89 | IDO1 (0.54) | IDO1TDO2IDO2CYP3A4CYP2C9 | |
| SCHEMBL20199267 | 0.88 | IDO1 (0.48) | IDO1CYP3A4CYP2C9 | |
| SCHEMBL20199153 | 0.87 | IDO1 (0.49) | IDO1TDO2IDO2CYP3A4CYP2C9 | |
| SCHEMBL20199308 | 0.87 | IDO1 (0.52) | IDO1TDO2IDO2CYP3A4CYP2C9 | |
| SCHEMBL30141305 | 0.86 | IDO1 (0.67) | IDO1TDO2IDO2CYP3A4CYP2C9 | |
| SCHEMBL20090679 | 0.86 | IDO1 (0.67) | IDO1TDO2IDO2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560914-A1 | SULFONYL AMIDINE AS INDOLEAMINE-2,3-DIOXYGENASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Longwood Biopharmaceuticals Co., Ltd. (CN) | 2019-10-30 | — | — | EP | disclosed |
| WO-2018095432-A1 | SULFOXIMINE, SULFONIMIDAMIDE, SULFONDIIMINE AND DIIMIDOSULFONAMIDE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2, 3-DIOXYGENASE | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2018-05-31 | — | — | WO | disclosed |