Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20199121 | 0.88 | IDO1 (0.52) | IDO1CYP3A4CYP2C9 | |
| SCHEMBL20199192 | 0.88 | MEN1 (0.48) | IDO1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL20199153 | 0.87 | IDO1 (0.49) | IDO1CYP3A4CYP2C9 | |
| SCHEMBL19900662 | 0.86 | IDO1 (0.51) | IDO1CYP3A4CYP2C9 | |
| SCHEMBL19900660 | 0.86 | IDO1 (0.51) | IDO1CYP3A4CYP2C9 | |
| SCHEMBL19661023 | 0.86 | IDO1 (0.51) | IDO1CYP3A4CYP2C9 | |
| SCHEMBL20199306 | 0.85 | IDO1 (0.41) | IDO1CYP3A4CYP2C9 | |
| SCHEMBL21188374 | 0.85 | IDO1 (0.65) | IDO1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19465774 | 0.84 | IDO1 (0.58) | IDO1CYP3A4CYP2C9 | |
| SCHEMBL146606 | 0.84 | IDO1 (0.58) | IDO1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018095432-A1 | SULFOXIMINE, SULFONIMIDAMIDE, SULFONDIIMINE AND DIIMIDOSULFONAMIDE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2, 3-DIOXYGENASE | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2018-05-31 | — | — | WO | disclosed |