SCHEMBL20199559

SCHEMBL20199559

c1ccc2c(c1)-c1ccccc1C21c2ccccc2C2(c3ccccc3-c3c2ccc2c4ccccc4n(-c4ccc5oc6ccccc6c5c4)c32)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15840148 0.99 AHR (0.33) AHRKDM4EMEN1NPC1ALDH1A1
SCHEMBL17381209 0.93 AHR (0.30) AHRKDM4EMEN1NPC1ALDH1A1
SCHEMBL19472151 0.89 NPSR1 (0.33) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL17637772 0.89 NPSR1 (0.33) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL26286301 0.88 DUSP3 (0.31)
SCHEMBL22140774 0.88
SCHEMBL20199713 0.88 SIRT2 (0.33) AHRKDM4EMEN1NPC1ALDH1A1
SCHEMBL17245771 0.87 KDM4E (0.32) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL15832286 0.86
SCHEMBL20199704 0.86 TDP1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-05-11 US disclosed
EP-3305764-B1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2019-09-25 EP disclosed
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same DCX, TERT, TELO2 AHR 2186/4885KDM4E 1392/4885MEN1 2052/4885
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME DCX, TERT, TELO2 AHR 2186/4885KDM4E 1392/4885MEN1 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.