Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069400 | 0.92 | KMT2A (0.40) | KMT2AMEN1KDM4EMDM2ALDH1A1 | |
| SCHEMBL22112591 | 0.89 | — | — | |
| SCHEMBL22112589 | 0.87 | KDM4E (0.31) | KDM4EALDH1A1 | |
| SCHEMBL22112422 | 0.86 | HSD17B10 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL23656479 | 0.85 | KMT2A (0.37) | KMT2AMEN1KDM4EMDM2ALDH1A1 | |
| SCHEMBL20199781 | 0.84 | — | — | |
| SCHEMBL22112574 | 0.83 | HDAC1 (0.39) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL22112106 | 0.81 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL20188963 | 0.81 | NPSR1 (0.32) | KMT2AMEN1KDM4EMDM2ALDH1A1 | |
| SCHEMBL28858869 | 0.80 | NPSR1 (0.32) | KMT2AMEN1KDM4EMDM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544964-B1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma AG (DE) | 2020-06-17 | — | — | EP | disclosed |
| WO-2018096082-A1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | WO | disclosed |