Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187624 | 0.87 | HSD17B10 (0.37) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL20188998 | 0.81 | KDM4E (0.48) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL29834060 | 0.80 | KDM4E (0.47) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL20200101 | 0.77 | HSD17B10 (0.39) | KDM4EMDM2ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL20188963 | 0.77 | NPSR1 (0.32) | KDM4EMDM2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20187511 | 0.76 | CA1 (0.33) | KDM4EMDM2ALDH1A1SIGMAR1CA12 | |
| SCHEMBL28858869 | 0.76 | NPSR1 (0.32) | KDM4EMDM2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15496587 | 0.75 | HSD17B10 (0.44) | KDM4EALDH1A1SIGMAR1HSD17B10S1PR1 | |
| SCHEMBL20200029 | 0.75 | ALDH1A1 (0.33) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL29700458 | 0.73 | KDM4E (0.53) | KDM4EMDM2ALDH1A1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544964-B1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma AG (DE) | 2020-06-17 | — | — | EP | disclosed |
| WO-2018096082-A1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | WO | disclosed |