Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20200535 | 0.78 | APLNR (0.62) | APLNR | |
| SCHEMBL22810385 | 0.77 | APLNR (0.67) | APLNR | |
| SCHEMBL20200841 | 0.75 | APLNR (0.58) | APLNR | |
| SCHEMBL22810475 | 0.75 | APLNR (0.70) | APLNR | |
| SCHEMBL20200299 | 0.74 | APLNR (0.68) | APLNR | |
| SCHEMBL20200182 | 0.74 | APLNR (0.62) | APLNR | |
| SCHEMBL20189404 | 0.74 | APLNR (1.00) | APLNR | |
| SCHEMBL20190589 | 0.73 | APLNR (0.52) | APLNRTSHR | |
| SCHEMBL22810467 | 0.73 | APLNR (0.44) | APLNRTSHR | |
| SCHEMBL22810369 | 0.72 | APLNR (0.70) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097944-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |