Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402820 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2CNR1CNR2APLNRCHRM3 | |
| SCHEMBL12262390 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2CNR1CNR2APLNRRPS6KB2 | |
| SCHEMBL17976182 | 0.76 | ESR1 (0.34) | SMN1; SMN2CNR1CNR2APLNRRPS6KB2 | |
| SCHEMBL16019421 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2CNR1CNR2CHRM3TSHR | |
| SCHEMBL73299 | 0.72 | — | — | |
| SCHEMBL94414 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2CNR1CNR2CHRM3TSHR | |
| SCHEMBL13706022 | 0.72 | CNR1 (0.47) | SMN1; SMN2CNR1CNR2CHRM3TSHR | |
| SCHEMBL12238620 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2CNR1CNR2APLNRCHRM3 | |
| SCHEMBL10797758 | 0.71 | CHRM3 (0.34) | SMN1; SMN2CNR1CNR2APLNRCHRM3 | |
| SCHEMBL23573882 | 0.70 | SMN1; SMN2 (0.40) | SMN1; SMN2CNR1CNR2CHRM3RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |