Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20437918 | 0.99 | PARP10 (0.41) | ACACBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20376266 | 0.97 | ACACB (0.41) | ACACBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11951596 | 0.94 | ACACB (0.45) | ACACBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20204598 | 0.88 | DUT (0.43) | BCHEACHEL3MBTL1 | |
| SCHEMBL10289755 | 0.87 | BCHE (0.43) | PARP10BCHEACHEL3MBTL1 | |
| SCHEMBL25053730 | 0.85 | DUT (0.43) | PARP10 | |
| SCHEMBL13877384 | 0.82 | ACACB (0.44) | ACACBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL879007 | 0.82 | DUT (0.47) | PDE4B | |
| Hydrochloric Acid SCHEMBL4234257 | 0.81 | ACACB (0.43) | ACACBPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL30806083 | 0.81 | ACACB (0.43) | ACACBPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |