Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 6/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.55 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.55 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201653 | 1.00 | CHRNB4 (0.56) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL21533930 | 0.84 | CHRNB2 (0.54) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL13861974 | 0.84 | CHRNB4 (0.56) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL10196599 | 0.84 | CHRNB4 (0.71) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL15948903 | 0.84 | CHRNB4 (0.56) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL20201725 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL21324925 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL21324916 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL10873425 | 0.82 | CHRNB2 (0.59) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL2035662 | 0.81 | CHRNB4 (0.56) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098208-A1 | NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |