SCHEMBL20201709

SCHEMBL20201709

CC(C)COc1cc(C(C)(C)NCCCC/C=C/CN2CC(=O)NC2=O)ccc1F

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 16/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20207582 0.87 DUT (0.61) DUT
SCHEMBL31262584 0.84 DUT (0.64) DUT
SCHEMBL20188080 0.84 DUT (0.64) DUT
SCHEMBL20207688 0.83 DUT (0.52) DUT
SCHEMBL20201496 0.82 DUT (0.51) DUT
SCHEMBL20201926 0.81 DUT (0.50) DUT
SCHEMBL20189322 0.79 DUT (0.57) DUT
SCHEMBL21522649 0.79 DUT (0.57) DUT
SCHEMBL20376446 0.77 DUT (0.35) DUT
SCHEMBL20361926 0.76 DUT (0.54) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018098206-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed
WO-2018098207-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed