⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23224166 | 0.76 | DAO (0.43) | — | |
| SCHEMBL16470895 | 0.73 | CRBN (0.38) | — | |
| SCHEMBL3584096 | 0.72 | — | — | |
| SCHEMBL28144922 | 0.70 | YTHDF2 (0.48) | — | |
| SCHEMBL45882 | 0.67 | DAO (0.43) | — | |
| SCHEMBL13320099 | 0.67 | — | — | |
| SCHEMBL4379055 | 0.67 | DAO (0.43) | — | |
| SCHEMBL6889351 | 0.67 | CRBN (0.40) | — | |
| SCHEMBL2986044 | 0.67 | DAO (0.46) | — | |
| SCHEMBL27891346 | 0.67 | CRBN (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105553-A1 | BICYCLIC HETEROCYCLES AND THEIR USE AS WRN INHIBITORS | NOVARTIS AG (CH) | 2024-05-23 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |