Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.50 |
| ▸ | FLT1 | P17948 | 3/20 | 0.50 |
| ▸ | FLT4 | P35916 | 3/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 5/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765009 | 0.89 | GRM2 (0.43) | SLC6A2SLC6A4SLC6A3HTR1AEGFR | |
| SCHEMBL13419304 | 0.88 | EGFR (0.53) | SLC6A2SLC6A4SLC6A3HTR1AEGFR | |
| SCHEMBL1475712 | 0.86 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3HTR1ATDP1 | |
| SCHEMBL20376236 | 0.86 | GRM2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1AEGFR | |
| SCHEMBL24153920 | 0.86 | SCN9A (0.43) | SLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL1474704 | 0.85 | TDP1 (0.49) | SLC6A2SLC6A4SLC6A3HTR1AEGFR | |
| SCHEMBL20204766 | 0.85 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3HTR1AEGFR | |
| SCHEMBL765039 | 0.85 | SCN9A (0.44) | SLC6A4 | |
| SCHEMBL20206745 | 0.82 | GRM2 (0.47) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL13594935 | 0.82 | MAP2K1 (0.47) | SLC6A2SLC6A4SLC6A3HTR1AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |