Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 19/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202004 | 0.89 | DUT (0.43) | DUT | |
| SCHEMBL20201511 | 0.88 | DUT (0.43) | DUT | |
| SCHEMBL20202003 | 0.86 | DUT (0.43) | DUT | |
| SCHEMBL20201510 | 0.85 | DUT (0.44) | DUT | |
| SCHEMBL20201629 | 0.84 | DUT (0.46) | DUT | |
| SCHEMBL20201607 | 0.83 | DUT (0.41) | DUT | |
| SCHEMBL20201998 | 0.83 | DUT (0.43) | DUT | |
| SCHEMBL20201512 | 0.83 | DUT (0.43) | DUT | |
| SCHEMBL20201663 | 0.82 | DUT (0.41) | DUT | |
| SCHEMBL20201609 | 0.82 | DUT (0.41) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |