⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2475313 | 0.98 | — | — | |
| SCHEMBL2053934 | 0.75 | — | — | |
| SCHEMBL2291982 | 0.74 | KDM4E (0.30) | — | |
| SCHEMBL11353633 | 0.67 | — | — | |
| SCHEMBL1274829 | 0.65 | — | — | |
| SCHEMBL959308 | 0.65 | — | — | |
| SCHEMBL10365025 | 0.64 | — | — | |
| SCHEMBL2357161 | 0.62 | — | — | |
| SCHEMBL3519958 | 0.62 | — | — | |
| SCHEMBL28980646 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212634-A1 | COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE | OREGON STATE UNIVERSITY (US) | 2017-09-06 | — | — | EP | claimed |
| WO-2016069780-A1 | COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE | OREGON STATE UNIVERSITY (US) | 2016-05-06 | — | — | WO | claimed |
| EP-4634169-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | Pfizer Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| EP-3212634-A1 | COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE | OREGON STATE UNIVERSITY (US) | 2017-09-06 | — | — | EP | disclosed |
| CN-103517902-B | Methods and compositions for treating beta-thalassemia and sickle disease | 中央研究院 | 2016-09-21 | — | — | CN | disclosed |
| WO-2016069780-A1 | COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE | OREGON STATE UNIVERSITY (US) | 2016-05-06 | — | — | WO | disclosed |
| US-20130109817-A1 | Modified Polymers for Delivery of Polynucleotides, Method of Manufacture, and Methods of Use Thereof | MERSANA THERAPEUTICS, INC. (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2553019-A1 | MODIFIED POLYMERS FOR DELIVERY OF POLYNUCLEOTIDES, METHOD OF MANUFACTURE, AND METHODS OF USE THEREOF | Mersana Therapeutics, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| US-8349308-B2 | Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof | MERSANA THERAPEUTICS, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-8343977-B2 | Substituted triazolo-pyrimidine compounds | ARQULE, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| US-8329705-B2 | Substituted triazolo-pyrazine compounds | ARQULE, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20110243880-A1 | MODIFIED POLYMERS FOR DELIVERY OF POLYNUCLEOTIDES, METHOD OF MANUFACTURE, AND METHODS OF USE THEREOF | MERSANA THERAPEUTICS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2011120053-A1 | MODIFIED POLYMERS FOR DELIVERY OF POLYNUCLEOTIDES, METHOD OF MANUFACTURE, AND METHODS OF USE THEREOF | MERSANA THERAPEUTICS, INC. (US) | 2011-09-29 | — | — | WO | disclosed |
| WO-2011082267-A2 | SUBSTITUTED TRIAZOLO-PYRAZINE COMPOUNDS | ARQULE, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082271-A2 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS | ARQULE, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20110160226-A1 | Substituted Triazolo-Pyrimidine Compounds | ARQULE, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110160215-A1 | Substituted Triazolo-Pyrazine Compounds | ARQULE, INC. (US) | 2011-06-30 | — | — | US | disclosed |