⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980646 | 0.98 | — | — | |
| SCHEMBL28871737 | 0.76 | — | — | |
| Indoline SCHEMBL11158276 | 0.75 | PDPK1 (0.35) | — | |
| SCHEMBL28779041 | 0.72 | MAOA (0.31) | — | |
| SCHEMBL6889340 | 0.71 | — | — | |
| SCHEMBL9588590 | 0.70 | — | — | |
| SCHEMBL16927553 | 0.70 | — | — | |
| SCHEMBL30530546 | 0.70 | — | — | |
| SCHEMBL1396296 | 0.69 | — | — | |
| SCHEMBL4721785 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310775-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-04-25 | — | — | EP | claimed |
| WO-2016202755-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | claimed |
| EP-0980374-A1 | PHOSPHODIESTERASE 4-INHIBITING DIAZEPINOINDOLONES | PARKE-DAVIS (FR) | 2000-02-23 | — | — | EP | claimed |
| WO-1999050270-A1 | PHOSPHODIESTERASE IV-INHIBITING DIAZEPINOINDOLES | PARKE-DAVIS (FR) | 1999-10-07 | — | — | WO | claimed |
| WO-1998049169-A1 | PHOSPHODIESTERASE 4-INHIBITING DIAZEPINOINDOLONES | PARKE-DAVIS (FR) | 1998-11-05 | — | — | WO | claimed |
| JP-6298727-A | — | — | None | — | — | JP | disclosed |
| US-12611417-B1 | Compositions and methods to inhibit acid-catalyzed dephosphorylation of phosphoryloxytryptamines | Convergent Health Sciences LLC: (US) | 2026-04-28 | — | — | US | disclosed |
| US-12503713-B1 | Stabilization of tryptamines by denaturing enzymes, optimizing ionization states, and controlling confounding variables | Convergent Health Sciences LLC (US) | 2025-12-23 | — | — | US | disclosed |
| US-12497637-B1 | Stabilization of tryptamines by denaturing enzymes, optimizing ionization states, and controlling confounding variables | Convergent Health Sciences LLC (US) | 2025-12-16 | — | — | US | disclosed |
| CN-120053679-A | CD66 c-targeted antibody coupling drug and application thereof in preparation of gastroesophageal junction cancer treatment drug | 浙江省肿瘤医院 | 2025-05-30 | — | — | CN | disclosed |
| CN-111655258-B | Compositions for cryopreservation and methods of use thereof | 常青树生物科学公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119587713-A | Use of a substance specifically binding ICAM1 for the preparation of a tongue cancer treatment product | 中国科学院基础医学与肿瘤研究所(筹) | 2025-03-11 | — | — | CN | disclosed |
| EP-0680964-A1 | NEW PIRROLO 3,2-e]INDOL DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND APPLICATIONS | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 1995-11-08 | — | — | EP | disclosed |
| JP-H06298727-A | PRODUCTION OF CYCLIC AMINES | NEW JAPAN CHEM CO LTD | 1994-10-25 | — | — | JP | disclosed |
| EP-0162695-B1 | 6-OXYGENATED-1,3,,4,5-TETRAHYDROBENZ(CD)INDOL-4-AMINES | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-17 | — | — | EP | disclosed |
| US-4824965-A | 4-oxo-4,5,6,7-Tetrahydroindole derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1989-04-25 | — | — | US | disclosed |
| US-4824965-A | 4-oxo-4,5,6,7-Tetrahydroindole derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1989-04-25 | — | — | US | disclosed |
| US-4736043-A | Process for the preparation of indole derivatives | BOEHRINGER MANNEHEIM GMBH (DE) | 1988-04-05 | — | — | US | disclosed |
| EP-0162695-A1 | 6-Oxygenated-1,3,,4,5-Tetrahydrobenz(cd)indol-4-amines | SMITHKLINE BEECHAM CORPORATION (US) | 1985-11-27 | — | — | EP | disclosed |
| US-4079006-A | USING A PHOSPHONOMETHYLENE-AMINO CARBOXYLATE | MONSANTO COMPANY (US) | 1978-03-14 | — | — | US | disclosed |