SCHEMBL20202168

SCHEMBL20202168

O=C(O)CCC(NC(=O)NC(CCC(=O)NC(CCCCNC(=O)CCC(NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)NC(CCCCNC(=O)CCCc1ccc(I)cc1)C(=O)O)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 3/20 0.74
▸ FOLH1 Q04609 17/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202217 0.98 ALB (0.71) ALBFOLH1
SCHEMBL22466348 0.97 ALB (0.69) ALBFOLH1
SCHEMBL22488669 0.97 ALB (0.69) ALBFOLH1
SCHEMBL20202173 0.94 FOLH1 (0.68) ALBFOLH1
SCHEMBL20202167 0.89 FOLH1 (0.63) ALBFOLH1
SCHEMBL19743100 0.88 ALB (0.72) ALBFOLH1
SCHEMBL19743101 0.88 ALB (0.72) ALBFOLH1
SCHEMBL31476046 0.87 FOLH1 (0.78) ALBFOLH1
SCHEMBL24910517 0.85 FOLH1 (0.75) ALBFOLH1
SCHEMBL19743080 0.85 ALB (0.77) ALBFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11147889-B2 Albumin-binding PSMA inhibitors CANCER TARGETED TECHNOLOGY LLC (US) 2021-10-19 — — US disclosed
US-20200061218-A1 Albumin-Binding PSMA Inhibitors CANCER TARGETED TECHNOLOGY LLC 2020-02-27 — — US disclosed
WO-2018098390-A1 ALBUMIN-BINDING PSMA INHIBITORS CANCER TARGETED TECHNOLOGY LLC (US) 2018-05-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11147889-B2 Albumin-binding PSMA inhibitors PSMA1, ALB, PSMA2 ALB 2/4885FOLH1 4/4885
US-20200061218-A1 Albumin-Binding PSMA Inhibitors PSMA1, ALB, PSMA2 ALB 2/4885FOLH1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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