SCHEMBL20202173

SCHEMBL20202173

O=C(O)CCC(NC(=O)NC(CCCCNC(=O)CCCCCCC(=O)NCCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)CCC(NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)NC(CCCCNC(=O)CCCc1ccc(I)cc1)C(=O)O)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 19/20 0.68
▸ ALB P02768 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202167 0.95 FOLH1 (0.63) FOLH1ALB
SCHEMBL20202217 0.94 ALB (0.71) FOLH1ALB
SCHEMBL22488669 0.94 ALB (0.69) FOLH1ALB
SCHEMBL22466348 0.94 ALB (0.69) FOLH1ALB
SCHEMBL20202168 0.94 ALB (0.74) FOLH1ALB
SCHEMBL18807597 0.91 FOLH1 (0.79) FOLH1
SCHEMBL18659693 0.91 FOLH1 (0.79) FOLH1
SCHEMBL1392836 0.91 FOLH1 (0.79) FOLH1
SCHEMBL19389387 0.91 FOLH1 (0.79) FOLH1
SCHEMBL418555 0.90 FOLH1 (0.78) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11147889-B2 Albumin-binding PSMA inhibitors CANCER TARGETED TECHNOLOGY LLC (US) 2021-10-19 — — US disclosed
US-20200061218-A1 Albumin-Binding PSMA Inhibitors CANCER TARGETED TECHNOLOGY LLC 2020-02-27 — — US disclosed
WO-2018098390-A1 ALBUMIN-BINDING PSMA INHIBITORS CANCER TARGETED TECHNOLOGY LLC (US) 2018-05-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11147889-B2 Albumin-binding PSMA inhibitors PSMA1, ALB, PSMA2 FOLH1 4/4885ALB 2/4885
US-20200061218-A1 Albumin-Binding PSMA Inhibitors PSMA1, ALB, PSMA2 FOLH1 4/4885ALB 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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