Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 4/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202346 | 0.83 | NISCH (0.42) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL20202344 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BF10 | |
| SCHEMBL23902184 | 0.77 | NISCH (0.46) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL23902266 | 0.70 | NISCH (0.53) | NISCHMAOAMAOB | |
| SCHEMBL23901777 | 0.70 | NISCH (0.43) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL23902159 | 0.70 | NISCH (0.52) | NISCHF10 | |
| SCHEMBL23901778 | 0.69 | F2 (0.52) | — | |
| SCHEMBL23901776 | 0.69 | NISCH (0.42) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL23901824 | 0.68 | PRSS1 (0.53) | NISCH | |
| SCHEMBL4703727 | 0.68 | NISCH (0.58) | NISCHGAATSHRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | NIPPON SODA CO., LTD. (JP) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | GUCY1A2, GUCY1B2, GUCY1A1 | NISCH 1494/4885GAA 217/4885TSHR 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.