SCHEMBL20202936

SCHEMBL20202936

CCc1ccc(-c2cc(F)c(OCc3ccc4c(F)c(F)c(F)cc4c3)c(F)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 4/20 0.35
KDM1A O60341 1/20 0.35
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
MAOB P27338 1/20 0.32
ESR1 P03372 3/20 0.32
ESR2 Q92731 3/20 0.32
FAAH O00519 1/20 0.30
F10 P00742 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202962 1.00 FFAR4 (0.35) FFAR4KDM1ALMNAPOLBL3MBTL1
SCHEMBL20202960 0.92 FFAR4 (0.33) FFAR4KDM1AESR1ESR2
SCHEMBL20202952 0.91 FFAR4 (0.34) FFAR4KDM1AMAOAACHEMAOB
SCHEMBL20202937 0.91 FFAR4 (0.34) FFAR4KDM1AMAOAACHEMAOB
SCHEMBL20202953 0.89 RARB (0.39) FFAR4L3MBTL1
SCHEMBL20202942 0.89 RARB (0.39) FFAR4L3MBTL1
SCHEMBL20202963 0.88 RARB (0.43) FFAR4LMNAACHEESR1MAPT
SCHEMBL20202947 0.88 RARB (0.43) FFAR4LMNAACHEESR1MAPT
SCHEMBL20202938 0.87 ESR1 (0.38) FFAR4KDM1AMAOAACHEMAOB
SCHEMBL20202954 0.86 KDM1A (0.35) FFAR4KDM1AMAOAACHEMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed